The Syndrome X reference article from the English Wikipedia on 24-Apr-2004 (provided by Fixed Reference: snapshots of Wikipedia from wikipedia.org)

Syndrome X

Syndrome X (or: metabolic syndrome X) is a medical condition that affects a large number of people. In some studies, the prevalence in the USA is calculated as being up to 25% of the population.

Symptoms are:

• High blood pressure;
• Central obesity and difficulty losing weight;
• High cholesterol (combined hyperlipidemia);
• Insulin resistance and/or type II diabetes.

Associated diseases are:

• Polycystic ovarian syndrome;
• Hemochromatosis;
• Acanthosis nigricans;
• Non-alcoholic steatohepatitis

Other terms for this condition include CHAOS (originally Australian) and Reaven's Syndrome, after Dr Gerald M. Reaven (who put the syndrome on the map in 1988 in the Banting lecture).

Syndrome X is not related to the fragile X syndrome, a chromosomal abnormality. There is also a cardiac syndrome X, a subtype of angina pectoris where there is cardiac ischemia on exercise testing but no causative atherosclerosis on a coronary angiogram.

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