The Lupus Erythematosus reference article from the English Wikipedia on 24-Apr-2004
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Lupus Erythematosus

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Lupus Erythematosus (also known as Systemic Lupus Erythematosus - SLE) is an autoimmune disorder where antibodies are created against the body's own DNA.

Like some other autoimmune diseases, it affects mostly women and its cause is unknown. It can present with a characteristic butterfly-shaped rash of the face, causing a wolf-like appearance (lupus is Latin for wolf).

The immune system becomes hyperactive and attacks normal tissue. Lupus is a chronic disease; there are some treatments for the symptoms, but no cure is known. In lupus, autoimmune attacks result in inflammation, which in turn brings about a variety of symptoms.

Other symptoms include arthralgia (more often than frank arthritis), kidney damage (nephritis), blood coagulation problems (such as lupus anticoagulans), as well as effects on the central nervous system, lungs, heart and blood vessels.

See also