The Low-molecular weight-heparin reference article from the English Wikipedia on 24-Apr-2004 (provided by Fixed Reference: snapshots of Wikipedia from wikipedia.org)

Low-molecular weight-heparin

In medicine, low-molecular weight-heparin (LMWH) is a class of medication used as an anticoagulant in diseases that feature thrombosis, as well as for prophylaxis in situations that lead to a high risk of thrombosis.

Its differences with unfractioned heparin are:

• No need for monitoring of the APTT coagulation parameter
• Possibly a smaller risk of bleeding
• Smaller risk of osteoporosis in long-time use
• Smaller risk of heparin-induced thrombocytopenia, a feared side-effect of heparin.

Makes of LMWHs include:

• Dalteparin
• Enoxiparin (Clexane ®)
• Nadroparin (Fraxiparin® and Fraxodi®)
• Several others

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