The Graft-versus-host disease reference article from the English Wikipedia on 24-Apr-2004 (provided by Fixed Reference: snapshots of Wikipedia from wikipedia.org)

Graft-versus-host disease

Graft-versus-host disease is a common complication of allogeneic bone marrow transplantation. After bone marrow transplantation, T cells that were present in the transplanted cell population as contaminants attack the tissues of the transplant recipient. Graft-versus-host disease can occur even when HLA-identical sibling are the donors. HLA-identical siblings often have genetically different proteins that can adversely activate the MHC-antigen surveillance system that protects the body from foreign invaders.

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