Glucokinase
Glucokinase is a
hexokinase enzyme involved in the first step of
glycolysis where
glucose is transformed into
glucose-6-phosphate (G6P). The energy required to phosphorylate glucose comes from one
ATP. Glucokinase is found in the
liver. In other parts of the body such as muscle or the brain, other
hexokinase catalyzes the same reaction. Hexokinase is inhibited by G6P so when the energy demand of the tissue is satisfied, glucose stops being used. In contrast to this, glucokinase is not inhibited by G6P.