The Addiction reference article from the English Wikipedia on 24-Apr-2004
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Addiction

Addiction is a term used to describe a strong compulsion to repeat a behavior regardless of its negative consequences. A person who is addicted is sometimes called an addict.

Many drugs or behaviors can precipitate a pattern of conditions recognized as addiction, which include a craving for more of the drug or behavior, increased tolerance to increased exposure, and withdrawal symptoms of pain or discomfort in the absence of the addictive stimulus. Most drugs and behaviors that have the potential to provide both pleasure and relief from pain pose a risk of dependency.

Table of contents
1 Diverse addictions
2 Methods of care
3 Diverse explanations
4 Physiological basis
5 Casual addiction
6 See also

Diverse addictions

Not all medical practitioners agree on what comprises addiction or dependency. Researchers, medical professionals and popular literature has discussed addictions of several sorts, including those to:

Eating disorders are also widely treated as addictions; they are often characterised by strong elements of addictive behaviour. Many people experience withdrawal or withdrawal-like symptoms if they alter their diet suddenly, suggesting that some common food substances - especially chocolate, artificial sweeteners, and sugar - may have the potential for addiction. But eating disorders are also sometimes related to other disfunctions outside the "pleasure centers" of the brain most commonly related to addiction.

The medical community usually distinguishes between physical and psychological addictions. Physical dependency leads to physical symptoms in the absence of the addictive substance whereas psychological dependency is related to psychological discomfort. The distinction does not necessarily mean that psychological addictions are easier to break than physical ones. Addictions often appear to have both physical and psychological components. Breaking any addiction can be difficult, otherwise it wouldn't be an addiction.

The speed with which a given individual becomes addicted to various substances varies with the substance, the frequency of use, the means of ingestion, and the individual. Some alcoholics say that they drank in an alcoholic way from the moment of first intoxication, while other people drink socially without ever becoming addicted. Nicotine is considered by many to be among the most most addictive substance in common use.

Methods of care

Early editions of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders described addiction as a physical dependancy on a substance that resulted in withdrawal symptoms in the absence of the substance. Recent editions, including DSM-IV, have moved toward a diagnostic instrument that classifies such conditions as dependency, rather than addiction. The American Society of Addiction Medicine recommends treatments for people with chemical dependancy based on patient placement criteria (currently listed in PPC-2), which attempt to match levels of care according to clinical assessments in six areas, including:

Some medical systems, including those of at least 15 states of the United States, refer to an Addiction Severity Index to assess the severity of problems related to substance use. The index asesses problems in six areas: medical, employment/support, alcohol and other drug use, legal, family/social, and psychiatric.

While addiction or dependency is related to seemingly uncontrollable urges, and may have roots in genetic predispositions, treatment of dependency is always classified as behavioral medicine. Early treatment of acute withdrawal often includes medical detoxification, which can include doses of anxiolitics to reduce symptoms of withdrawal. In chronic opiate addiction, a surrogate drug, such as methadone is sometimes offered as a form of opiate replacement therapy. But treatment approaches universally focus on the individual's ultimate choice to pursue an alternate course of action.

Therapists often classify patients with chemical dependencies as either interested in changing or not interested in change. Treatments usually involve planning for specific ways to avoid the addictive stimulus, and therapeutic interventions intended to help a client learn healthier ways to find satisfaction. Clinical leaders in recent years have attempted to tailor intervention approaches to specific influences that affect addictive behavior, using therapeutic interviews in an effort to discover factors that led a person to embrace unhealthy, addictive sources of pleasure or relief from pain.

Treatment Modality Matrix

Behavioral PatternInterventionGoals
Low self esteem, anxiety, verbal hostilityRelationship therapy, client centered approachIncrease self esteem, reduce hostility and anxiety
Defective personal constructs, ignorance of interpersonal meansCognitive restructuring including directive and group therapiesInsight
Focal anxiety such as fear of crowdsDesensitizationChange response to same cue
Undesirable behaviors, lacking appropriate behaviorsAversive conditioning, operant conditioning, counter conditioningEliminate or replace behavior
Lack of informationProvide informationHave client act on information
Difficult social circumstancesOrganizational intervention, environmental manipulation, family counselingRemove cause of social difficulty
Poor social performance, rigid interpersonal behaviorSensitivity training, communication training, group therapyIncrease interpersonal repetoire, desensitization to group functioning
Grossly bizarre behaviorMedical referralProtect from society, prepare for further treatment
Adapted from: Essentials of Clinical Dependency Counseling, Aspen Publishers

Diverse explanations

Several explanations (or "models") have been presented to explain addiction:

Physiological basis

Although the term addiction is sometimes often used loosely rather than as a medical classification, there are some physiological conditions related to everyday behaviors that are also related to the more commonly recognized mechanisms associated with addiction. Pleasurable activities cause the release of endorphins, and this endorphin-rush can conceivably become 'addictive'. This process of attentuating pleasure pathways is part of the brain's natural system for ensuring that humans develop abiding interests; since human societies depend on this, such addictions are not necessarily a problem. The pathways oriented to endorphins, sometimes called pleasure centers originated in small organisms such as insects, which rely on the neurological system to help them find familiar sources of food.

In general terms, endorphins stimulate activity of the neurotransmitter dopamine. Increased dopamine activity is often met by an increase in the number of receptors sensitive to dopamine. This process is called upregulation. The increased number of receptors tends to result in reduced electrical activity along post-synaptic nerve pathways, unless some behavior or substance causes a continued high level of dopaminergic stimulation. The absence of a pleasurable sensation in conditions that were formally sufficient can cause a mild feeling of let-down after neurons have been upregulated. The increased requirement for dopamine to maintain electrical activity is the basis of both tolerance and withdrawal associated with addiction.

In cases of physical dependency on depressants of the central nervous system such as opiates, barbiturates, or alcohol, the absence of the substance leads to symptoms of sometimes severe physical discomfort. In these cases, a body has become so dependant on a chemical that it has stopped producing the necessary neurotransmitters required to maintain a comfortable status.

Opiates present extreme risks of physical dependency because they are chemically similar to endorphins, causing an upregulation of dopaminergic receptors without stimulation of the endorphin systems. Cocaine and amphetamines also pose risks associated with physical attenuation, cocaine for its chemical similarity with dopamine, and amphetamines by their similarity with norepinephrine which acts indirectly to stimulate dopaminergic pathways in the brain.

Casual addiction

The word addiction is also sometimes used colloquially to refer to something a person has a passion for. Such "addicts" include:

See also